Michael Van Meter

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

Zhiyong Mao, Christopher Hine, Xiao Tian et al. · Science · 2011 · 850 citations · Full text

LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation

Matthew Simon, Michael Van Meter, Julia Ablaeva et al. · Cell Metabolism · 2019 · 473 citations · Full text

Inflammation, Lifespan Extension, Autoimmune Disease +11

SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age

Michael Van Meter, Mehr Kashyap, Sarallah Rezazadeh et al. · Nature Communications · 2014 · 425 citations · Full text

Natural Sciences, Genetics, Gene Regulation +7

Common and rare variant associations with clonal haematopoiesis phenotypes

Michael D. Kessler, Amy Damask, Sean O’Keeffe et al. · Nature · 2022 · 281 citations · Full text

Allelic Variant, Rare Variant Associations, Hematology +2

Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence

Zhiyong Mao, Xiao Tian, Michael Van Meter et al. · Proceedings of the National Academy of Sciences · 2012 · 176 citations · Full text