Michael Oestergaard

Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins

Michael T. Migawa, Wen Shen, Wei Wan et al. · Nucleic Acids Research · 2019 · 119 citations · Full text

Signal Transduction, Biochemistry, Site-specific Replacement +11

Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging

Curt Mazur, Berit Powers, Kenneth Zasadny et al. · JCI Insight · 2019 · 99 citations · Full text

It Pk, Social Sciences, Brain Pharmacology +18

Mechanisms of palmitic acid-conjugated antisense oligonucleotide distribution in mice

Alfred E. Chappell, Hans Gaus, Andrés Berdeja et al. · Nucleic Acids Research · 2020 · 57 citations · Full text

Muscle Tissue, Fcrn Knockout, Biochemistry +15

Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate

Noriko Satake, Connie P.M. Duong, Sakiko Yoshida et al. · Molecular Medicine · 2016 · 40 citations · Full text

MXD3 antisense oligonucleotide with superparamagnetic iron oxide nanoparticles: A new targeted approach for neuroblastoma

Sakiko Yoshida, Connie P.M. Duong, Michael Oestergaard et al. · Nanomedicine Nanotechnology Biology and Medicine · 2019 · 23 citations · Full text

Nanoparticles, Magnetism, Nanomedicine +10