Tom Kirrane

Ligands for the Tyrosine Kinase p56<i>^lck</i> SH2 Domain:  Discovery of Potent Dipeptide Derivatives with Monocharged, Nonhydrolyzable Phosphate Replacements

Pierre L. Beaulieu, Dale R. Cameron, Jean‐Marie Ferland et al. · Journal of Medicinal Chemistry · 1999 · 57 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Substituted pyrazoles as novel sEH antagonist: Investigation of key binding interactions within the catalytic domain

Ho Yin Lo, Chuk C. Man, Roman Fleck et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Identification of dissociated non-steroidal glucocorticoid receptor agonists

Daniel Kuzmich, Tom Kirrane, John Proudfoot et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 34 citations · Full text

Life Sciences, Endocrinology, Pharmacology +12

Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria

Benjamin R. Taft, Fumiaki Yokokawa, Tom Kirrane et al. · Journal of Medicinal Chemistry · 2022 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Practical synthesis of 1,3-diaryl-5-alkylpyrazoles by a highly regioselective N-arylation of 3,5-disubstituted pyrazoles with 4-fluoronitrobenzene

Xiao‐jun Wang, Jonathan Tan, Karl Grozinger et al. · Tetrahedron Letters · 2000 · 31 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10