Jean‐Marie Ferland

Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans

Anne‐Marie Faucher, Murray D. Bailey, Pierre L. Beaulieu et al. · Organic Letters · 2004 · 103 citations

Medicinal Chemistry, Ns3 Protease Inhibitor, Medicine +13

Synthesis of derivatives of isoindole and of pyrazino[2,1-<i>a</i>]isoindole

Jean‐Marie Ferland, Christopher A. Demerson, Leslie G. Humber · Canadian Journal of Chemistry · 1985 · 97 citations

Derivative (Chemistry), Derivatives, Biochemistry +9

Potent Inhibitors of the Hepatitis C Virus NS3 Protease:  Design and Synthesis of Macrocyclic Substrate-Based β-Strand Mimics

Nathalie Goudreau, Christian Brochu, Dale R. Cameron et al. · The Journal of Organic Chemistry · 2004 · 58 citations

Engineering, Protein Assembly, Biomolecular Structure Prediction +18

Ligands for the Tyrosine Kinase p56<i>^lck</i> SH2 Domain:  Discovery of Potent Dipeptide Derivatives with Monocharged, Nonhydrolyzable Phosphate Replacements

Pierre L. Beaulieu, Dale R. Cameron, Jean‐Marie Ferland et al. · Journal of Medicinal Chemistry · 1999 · 57 citations · Full text

Molecular Biology, Signal Transduction Events, Potent Dipeptide +17

Binding Mode Determination of Benzimidazole Inhibitors of the Hepatitis C Virus RNA Polymerase by a Structure and Dynamics Strategy

Steven R. LaPlante, Araz Jakalian, Norman Aubry et al. · Angewandte Chemie International Edition · 2004 · 52 citations

Viral Polymerase Structure, Molecular Biology, Mode Determination +19