Chuk C. Man

Structure-Based Optimization of Arylamides as Inhibitors of Soluble Epoxide Hydrolase

Anne B. Eldrup, Fariba Soleymanzadeh, Steven J. Taylor et al. · Journal of Medicinal Chemistry · 2009 · 69 citations · Full text

Lipid Peroxidation, Metabolomic Profiling, Structure-based Optimization +17

Substituted pyrazoles as novel sEH antagonist: Investigation of key binding interactions within the catalytic domain

Ho Yin Lo, Chuk C. Man, Roman Fleck et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 41 citations · Full text

Combinatorial Chemistry, Substituted Pyrazoles, Catalytic Domain +7

Influence of the β-Alkoxy Group on the Diastereoselectivity of Aldol Reactions of Tetrahydro-4<i>H</i>-thiopyran-4-one with 4-Alkoxytetrahydro-2<i>H</i>-thiopyran-3-carboxaldehydes

Dale E. Ward, Marcelo Magalhães Sales, Chuk C. Man et al. · The Journal of Organic Chemistry · 2002 · 40 citations

Engineering, Biochemistry, Anti-felkin Selectivity +12

Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design

Brian N. Cook, Jörg Bentzien, André White et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 33 citations · Full text

Drug Design, Medicine, Receptor Tyrosine Kinase +11

2-Aminobenzimidazoles as potent ITK antagonists: de novo design of a pyrrole system targeting additional hydrogen bonding interaction

Ho Yin Lo, Jörg Bentzien, André White et al. · Tetrahedron Letters · 2008 · 19 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9