Philip A. Carpino

Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms

Matthew F. Calabrese, Francis Rajamohan, Melissa S. Harris et al. · Structure · 2014 · 179 citations · Full text

Opposite Poles, Molecular Physiology, Signal Transduction +9

Results of surgical septal myectomy for obstructive hypertrophic cardiomyopathy: the Tufts experience

Hassan Rastegar, Griffin Boll, Ethan J. Rowin et al. · Annals of Cardiothoracic Surgery · 2017 · 116 citations · Full text

Enantiospecific total synthesis of pseudopterosins A and E

E. J. Corey, Philip A. Carpino · Journal of the American Chemical Society · 1989 · 101 citations

Biosynthesis, Bioorganic Chemistry, Molecular Sciences +15

A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation

Donna N. Petersen, Julie A. Hawkins, Wanida Ruangsiriluk et al. · Cell chemical biology · 2016 · 95 citations · Full text

Pcsk9 Targets, Protein Function, Signal Transduction +9

A potentiator of orthosteric ligand activity at GLP-1R acts via covalent modification

Whitney M. Nolte, Jean‐Philippe Fortin, Benjamin D. Stevens et al. · Nature Chemical Biology · 2014 · 85 citations

Molecular Pharmacology, Biochemistry, Functional Selectivity +9