Ross D. Hannan

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

Denis Drygin, Amy Lin, Josh Bliesath et al. · Cancer Research · 2010 · 621 citations

Life Sciences, Medicinal Chemistry, Oncology +17

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

Megan J. Bywater, Gretchen Poortinga, Elaine Sanij et al. · Cancer Cell · 2012 · 560 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF†

Katherine M. Hannan, Yves Brandenburger, Anna Jenkins et al. · Molecular and Cellular Biology · 2003 · 459 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

Lee H. Wong, James D. McGhie, Marcus Sim et al. · Genome Research · 2010 · 417 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere

Lee H. Wong, Kate H. Brettingham‐Moore, Lyn Chan et al. · Genome Research · 2007 · 294 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16