Concepedia

Nikolai Makukhin

NM

16

Publications

741

Citations

13

H-Index

2011

Active since

Affiliations

University of Dundee(Current)

Charles University

Lomonosov Moscow State University

Promega (United States)

University of Kansas

Nikolai Makukhin is an author at University of Dundee specializing in natural sciences, biochemistry, and molecular biology.

ORCID

Top concepts

Publications per year

2011–2024

16

Publications

16

Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

Satomi Imaide, Kristin M. Riching, Nikolai Makukhin et al. · Nature Chemical Biology · 2021 · 225 citations · Full text

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Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

Xingui Liu, Alexia F. Kalogeropulou, Sofia Domingos et al. · Journal of the American Chemical Society · 2022 · 152 citations · Full text

Mechanism of degrader-targeted protein ubiquitinability

Charlotte Crowe, Mark A. Nakasone, Sarah Chandler et al. · Science Advances · 2024 · 52 citations · Full text

A Ratiometric Fluorescent Probe for Imaging of the Activity of Methionine Sulfoxide Reductase A in Cells

Nikolai Makukhin, Vyacheslav Tretyachenko, Jackob Moskovitz et al. · Angewandte Chemie International Edition · 2016 · 46 citations

Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase

Wei-Wei Kung, Sarath Ramachandran, Nikolai Makukhin et al. · Nature Communications · 2019 · 39 citations · Full text

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