Nikolai Makukhin - Concepedia

Author

Nikolai Makukhin

Also Known As

Makukhin, Nikolay N., N N Makukhin, N. Makukhin, N. N. Makukhin, N.N. Makukhin, Nikolai Makukhin, Nikolay Makukhin, Nikolay N. Makukhin

Publications

800

Citations

H-Index

Concepts

All Affiliations

University of Dundee Charles University Lomonosov Moscow State University Promega (United States)University of Kansas

About

Nikolai Makukhin is an author at University of Dundee specializing in natural sciences, biochemistry, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	6	6	312
2	Biochemistry	5	5	284
3	Medicine	3	3	56
4	Engineering	1	1	13
5	Chemical Biology	1	1	11

Nikolai Makukhin

Publications

741

Citations

H-Index

Page 1

	Year	Citations
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity Satomi Imaide, Kristin M. Riching, Nikolai Makukhin, Nature Chemical Biology Protein ChemistryProtein FunctionBiochemistryProtein AssemblyProtein Folding	2021	225
Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2 Xingui Liu, Alexia F. Kalogeropulou, Sofia Domingos, Journal of the American Chemical Society	2022	152
Mechanism of degrader-targeted protein ubiquitinability Charlotte Crowe, Mark A. Nakasone, Sarah Chandler, Science Advances	2024	52
A Ratiometric Fluorescent Probe for Imaging of the Activity of Methionine Sulfoxide Reductase A in Cells Nikolai Makukhin, Vyacheslav Tretyachenko, Jackob Moskovitz, Angewandte Chemie International Edition	2016	46
Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase Wei-Wei Kung, Sarath Ramachandran, Nikolai Makukhin, Nature Communications	2019	39
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma Silvia Pietrobono, Eugenio Gaudio, Sinforosa Gagliardi, Oncogene	2021	38
Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2 Sarath Ramachandran, Nikolai Makukhin, Kevin Haubrich, Nature Communications	2023	35
Synthetic routes to 3(5)-phosphonylated pyrazoles Nataliya S. Goulioukina, Nikolai Makukhin, I. P. Beletskaya Russian Chemical Reviews Combinatorial ChemistryPhosphonate GroupDiversity Oriented SynthesisDerivativesHeterocyclic	2015	28
Leveraging Dual-Ligase Recruitment to Enhance Protein Degradation via a Heterotrivalent Proteolysis Targeting Chimera Adam G. Bond, Miquel Muñoz i Ordoño, Celia M. Bisbach, Journal of the American Chemical Society	2024	24
1,3-Dipolar cycloaddition of diazoalkanes onto dimethyl 1-(formylamino)ethylenephosphonate: a new route to 1-aminocyclopropanephosphonic acids and 3-phosphorylated pyrazoles Nataliya S. Goulioukina, Nikolai Makukhin, I. P. Beletskaya Tetrahedron 1-Aminocyclopropanephosphonic AcidsMedicinal ChemistryHeterocyclicBiochemistryNatural Sciences	2011	18

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