Alexia F. Kalogeropulou

Publications

410

Citations

H-Index

2018

Active since

Affiliations

MRC Protein Phosphorylation and Ubiquitylation Unit(Current)

University of Dundee

Michael J. Fox Foundation

Alexia F. Kalogeropulou is an author at MRC Protein Phosphorylation and Ubiquitylation Unit specializing in cell signaling, signal transduction, and medicine.

ORCID

Top concepts

MedicineCell BiologyCell SignalingSystems BiologyMolecular BiologySignal TransductionAutophagyPharmacologyGene ExpressionNatural Sciences

Publications per year

2018–2022

Publications

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

Xingui Liu, Alexia F. Kalogeropulou, Sofia Domingos et al. · Journal of the American Chemical Society · 2022 · 152 citations · Full text

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding

Alexia F. Kalogeropulou, Elena Purlyte, Francesca Tonelli et al. · Biochemical Journal · 2022 · 129 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +13

Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity

Alexia F. Kalogeropulou, Jordana B. Freemantle, Edmundo G. Vides et al. · Biochemical Journal · 2020 · 73 citations · Full text

Molecular Regulation, Endogenous Rab29, Molecular Biology +19

P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity

Alexia F. Kalogeropulou, Jing Zhao, Marc Bolliger et al. · Biochemical Journal · 2018 · 56 citations · Full text

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