Concepedia

Elena Purlyte

EP

8

Publications

782

Citations

8

H-Index

2017

Active since

Affiliations

MRC Protein Phosphorylation and Ubiquitylation Unit(Current)

University of Dundee

Research Network (United States)

Stanford University

Boston Children's Hospital

Elena Purlyte is an author at MRC Protein Phosphorylation and Ubiquitylation Unit specializing in medicine, cell signaling, and signal transduction.

ORCID

Top concepts

Publications per year

2017–2023

8

Publications

8

Rab29 activation of the Parkinson's disease‐associated LRRK2 kinase

Elena Purlyte, Herschel S. Dhekne, Adil R. Sarhan et al. · The EMBO Journal · 2017 · 359 citations · Full text

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding

Alexia F. Kalogeropulou, Elena Purlyte, Francesca Tonelli et al. · Biochemical Journal · 2022 · 129 citations · Full text

, , +13

Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2

Dieter Waschbüsch, Elena Purlyte, Prosenjit Pal et al. · Structure · 2020 · 93 citations · Full text

A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation

Edmundo G. Vides, Ayan Adhikari, Claire Y Chiang et al. · eLife · 2022 · 63 citations · Full text

, , +20

Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase

Herschel S. Dhekne, Francesca Tonelli, Wondwossen M Yeshaw et al. · eLife · 2023 · 62 citations · Full text

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