SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Matthew D. Hirschey, Tadahiro Shimazu, Eric S. Goetzman, +17

Nature

Mitochondrial FunctionBiochemistryMitochondrial Fatty-acid OxidationMetabolismMedicine +2

Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation

David B. Lombard, Frederick W. Alt, Hwei-Ling Cheng, +17

Molecular and Cellular Biology

Lifespan ExtensionSystems BiologySoluble Mitochondrial ProteinMitochondrial FunctionMitochondrial Dynamic +8

SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome

Matthew D. Hirschey, Tadahiro Shimazu, Enxuan Jing, +18

Molecular Cell

Metabolic SyndromeMetabolic DisorderMitochondrial FunctionSirt3 DeficiencyGenetics +8

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

Bjoern Schwer, Jakob Bunkenborg, Regis O. Verdin, +2

Proceedings of the National Academy of Sciences

Cellular EnzymologyBiochemistryMitochondrial FunctionMetabolic EnzymeNatural Sciences +12

SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production

Tadahiro Shimazu, Matthew D. Hirschey, Lan Hua, +9

Cell Metabolism

Mitochondrial FunctionBiochemistryNatural SciencesMitochondrial DynamicGene Expression +6

Regulation of Insulin Secretion by SIRT4, a Mitochondrial ADP-ribosyltransferase

Nidhi Ahuja, Bjoern Schwer, Stefania Carobbio, +5

Journal of Biological Chemistry

BiochemistryMitochondrial FunctionMitochondrial Sirt4MedicineDiabetes +11

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

Wataru Ise, Masako Kohyama, Barbara U. Schraml, +8

Nature Immunology

Cell RegulationT CellsGeneticsGene ExpressionB Cells +7

Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells

Pei‐Chi Wei, Amelia Chang, Jennifer Kao, +4

Cell

ChromatinGenome InstabilityNeuroregenerationMolecular NeuroscienceCell Lineage +10

Calorie restriction alters mitochondrial protein acetylation

Bjoern Schwer, Mark Eckersdorff, Yu Li, +7

Aging Cell

Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity

Bjoern Schwer, Björn Schumacher, David B. Lombard, +9

Proceedings of the National Academy of Sciences