Donald J. Cook

Discovery of a Novel Class of Dimeric Smac Mimetics as Potent IAP Antagonists Resulting in a Clinical Candidate for the Treatment of Cancer (AZD5582)

Edward J. Hennessy, Ammar Adam, Brian Aquila et al. · Journal of Medicinal Chemistry · 2013 · 112 citations · Full text

Compound 14, Apoptosis, Cell Death +18

The discovery of BMS-275183: an orally efficacious novel taxane

Harold Mastalerz, Donald J. Cook, Craig R. Fairchild et al. · Bioorganic & Medicinal Chemistry · 2003 · 47 citations

Biology, Natural Sciences, Molecular Biology +5

Identification of 3-amido-4-anilinoquinolines as potent and selective inhibitors of CSF-1R kinase

David A. Scott, Carrie L. Balliet, Donald J. Cook et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 37 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11

Discovery and Optimization of a Novel Series of Potent Mutant B-Raf^V600E Selective Kinase Inhibitors

Melissa M. Vasbinder, Brian Aquila, Martin Augustin et al. · Journal of Medicinal Chemistry · 2013 · 31 citations · Full text

Drug Target, Molecular Biology, Chemical Biology +20

Facile Synthesis of a Simplified Bicyclo[7.3.1] Esperamicin-Calicheamicin Enediyne Core

John F. Kadow, Donald J. Cook, Terrence W. Doyle et al. · Tetrahedron · 1994 · 28 citations

Pharmacology, Organic Chemistry, Synthetic Chemistry +1