Bernd Buettelmann

RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors

Theresa M. Ballard, Frédéric Knoflach, Eric Prinssen et al. · Psychopharmacology · 2008 · 152 citations

Novel Cognitive Enhancer, Medicine, Neurotransmitter +8

DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome

Hans Richter, Alexander L. Satz, Marc Bedoucha et al. · ACS Chemical Biology · 2018 · 110 citations · Full text

The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA α5 inverse agonists for the treatment of cognitive dysfunction

Henner Knust, Guido Achermann, Theresa M. Ballard et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 63 citations · Full text

Molecular Pharmacology, Medicine, Cognitive Dysfunction +8

Rational design, synthesis, and structure–activity relationship of benzoxazolones: New potent mglu5 receptor antagonists based on the fenobam structure

Simona Ceccarelli, Georg Jaeschke, Bernd Buettelmann et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 28 citations · Full text

Fenobam Structure, Molecular Pharmacology, Structure–activity Relationship +10

Design of Potent and Druglike Nonphenolic Inhibitors for Catechol <i>O</i>-Methyltransferase Derived from a Fragment Screening Approach Targeting the <i>S</i>-Adenosyl-<scp>l</scp>-methionine Pocket

C. Lerner, Roland Jakob‐Roetne, Bernd Buettelmann et al. · Journal of Medicinal Chemistry · 2016 · 28 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +15