Georg Jaeschke

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

Aubin Michalon, Michael S. Sidorov, Theresa M. Ballard et al. · Neuron · 2012 · 490 citations · Full text

Medicine, Neuroscience, Pharmacology +5

Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity

Richard H. Porter, Georg Jaeschke, Will Spooren et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 314 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor

Lothar Lindemann, Georg Jaeschke, Aubin Michalon et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 121 citations

Medicine, Neuroscience, Pharmacology +14

Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion

Di Tian, Laura J. Stoppel, Arnold J. Heynen et al. · Nature Neuroscience · 2015 · 112 citations · Full text

Life Sciences, Genetics, Neuroscience +8

Resolution of racemic carboxylic acid derivatives by Ti-TADDOLate mediated esterification reactions—A general method for the preparation of enantiopure compounds

Dieter Seebàch, Georg Jaeschke, Konstanze Gottwald et al. · Tetrahedron · 1997 · 103 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5