Daisuke Sugiyama

Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers

Takuro Saito, Hiroyoshi Nishikawa, Hisashi Wada et al. · Nature Medicine · 2016 · 861 citations

Tumor Biology, Colorectal Cancers, Medicine +8

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Shogo Kumagai, Shohei Koyama, Kota Itahashi et al. · Cancer Cell · 2022 · 752 citations

Cancer Immunosurveillance, Pd-1 Expression, Medicine +11

Anti-CCR4 mAb selectively depletes effector-type FoxP3⁺CD4⁺regulatory T cells, evoking antitumor immune responses in humans

Daisuke Sugiyama, Hiroyoshi Nishikawa, Yuka Maeda et al. · Proceedings of the National Academy of Sciences · 2013 · 608 citations · Full text

Significance Regulatory T, T-regulatory Cell, Immunology +24

Fecal microbiota transplantation for patients with steroid-resistant acute graft-versus-host disease of the gut

Kazuhiko Kakihana, Yuki Fujioka, Wataru Suda et al. · Blood · 2016 · 352 citations · Full text

Detection of self-reactive CD8 ⁺ T cells with an anergic phenotype in healthy individuals

Yuka Maeda, Hiroyoshi Nishikawa, Daisuke Sugiyama et al. · Science · 2014 · 204 citations