Yuka Maeda

Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

Naiyer A. Rizvi, Matthew D. Hellmann, Alexandra Snyder et al. · Science · 2015 · 7.8K citations · Full text

Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers

Takuro Saito, Hiroyoshi Nishikawa, Hisashi Wada et al. · Nature Medicine · 2016 · 861 citations

Tumor Biology, Colorectal Cancers, Medicine +8

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Shogo Kumagai, Yosuke Togashi, Takahiro Kamada et al. · Nature Immunology · 2020 · 785 citations

Cancer Immunosurveillance, Autoimmune Disease, T-regulatory Cell +12

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Shogo Kumagai, Shohei Koyama, Kota Itahashi et al. · Cancer Cell · 2022 · 752 citations

Cancer Immunosurveillance, Pd-1 Expression, Medicine +11

Anti-CCR4 mAb selectively depletes effector-type FoxP3⁺CD4⁺regulatory T cells, evoking antitumor immune responses in humans

Daisuke Sugiyama, Hiroyoshi Nishikawa, Yuka Maeda et al. · Proceedings of the National Academy of Sciences · 2013 · 608 citations · Full text

Significance Regulatory T, T-regulatory Cell, Immunology +24