Genome-wide copy number analysis of single cells

Timour Baslan, Jude Kendall, Linda Rodgers, +10

Nature Protocols

Functional GenomicsCell DivisionSingle Cell SequencingMedicineGenetics +7

Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory

François V. Bolduc, Kimberly Bell, Hilary Cox, +2

Nature Neuroscience

Genome InstabilityDevelopmental BiologyGeneticsFragile X SpectrumGenomic Mechanism +5

Optimizing sparse sequencing of single cells for highly multiplex copy number profiling

Timour Baslan, Jude Kendall, Brian Ward, +15

Genome Research

EngineeringGeneticsSingle CellsGenomicsHigh Throughput Sequencing +17

Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples

Luciano G. Martelotto, Timour Baslan, Jude Kendall, +20

Nature Medicine

Formalin-fixed Paraffin-embedded SamplesSingle Cell SequencingMedicineGeneticsSingle-cell Genomics +4

SOAT1 promotes mevalonate pathway dependency in pancreatic cancer

Tobiloba E. Oni, Giulia Biffi, Lindsey A. Baker, +18

The Journal of Experimental Medicine

Pdac ProgressionCholesterol MetabolismOxysterolPancreatic CancerMedicine +10

Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing

Timour Baslan, Jude Kendall, Konstantin Volyanskyy, +22

eLife

EngineeringGeneticsGenomicsCna HeterogeneityTumor Biology +17

TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

Debjani Pal, Anja Pertot, Nitin H. Shirole, +14

eLife

Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function

Manojit Mosur Swamynathan, Shan Kuang, Kaitlin Watrud, +42

Science

Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer

Joan Alexander, Jude Kendall, Jean McIndoo, +22

Cancer Research

ADRENALECTOMY AND PROSTATIC CARCINOMA

Hilary Cox

The Lancet

UrologySurgical OncologyMedicineSurgeryAdrenal Disease +2