Harvey E. Fries

Development of Dihydropyridone Indazole Amides as Selective Rho-Kinase Inhibitors

Krista Goodman, Haifeng Cui, Sarah E. Dowdell et al. · Journal of Medicinal Chemistry · 2006 · 154 citations · Full text

Indazole Substitution, Medicinal Chemistry, Oral Bioavailability +11

Sirtuin 1 activator <scp>SRT</scp>2104 protects Huntington's disease mice

Mali Jiang, Jennifer Zheng, Peng Qi et al. · Annals of Clinical and Translational Neurology · 2014 · 51 citations · Full text

Lifespan Extension, Transcriptional Regulation, Neurodegenerative Diseases +15

Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K)

Brian G. Lawhorn, Joanne Philp, Yongdong Zhao et al. · Journal of Medicinal Chemistry · 2015 · 46 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Signal Transduction +14

An excitatory role for peripheral EP ₃ receptors in bladder afferent function

Xin Su, Erin S. R. Lashinger, Lisa A. Leon et al. · American Journal of Physiology-Renal Physiology · 2008 · 32 citations

Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues

David J. Behm, John J. McAtee, Jason W. Dodson et al. · British Journal of Pharmacology · 2008 · 31 citations · Full text