A.E. Prota

Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents

A.E. Prota, Katja Bargsten, Didier Zurwerra et al. · Science · 2013 · 487 citations · Full text

Medicine, Molecular Mechanism, Cancer Cell Biology +12

The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization

A.E. Prota, Franck Danel, Felix Bachmann et al. · Journal of Molecular Biology · 2014 · 299 citations

Microtubule Organization, Protein Function, Molecular Biology +7

A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

A.E. Prota, Katja Bargsten, J. Fernando Dı́az et al. · Proceedings of the National Academy of Sciences · 2014 · 272 citations · Full text

Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons

Tobias Weinert, Natacha Olieric, R.K. Cheng et al. · Nature Communications · 2017 · 263 citations · Full text

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

Marco Jost, Yuwen Chen, Luke A. Gilbert et al. · Molecular Cell · 2017 · 251 citations · Full text

Engineering, Biotechnology, Synthetic Biology +8