The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization

A.E. Prota, Franck Danel, Felix Bachmann, +6

Journal of Molecular Biology

Microtubule OrganizationProtein FunctionMolecular BiologyColchicine SiteDistinct Effects +5

Development of a Virtual Screening Method for Identification of “Frequent Hitters” in Compound Libraries

Olivier Roche, Petra Schneider, Jochen Zuegge, +21

Journal of Medicinal Chemistry

EngineeringHit IdentificationPattern DiscoveryNonlinear Statistical MethodsMedicinal Chemistry +22

Crystal structure of the class D beta-lactamase OXA-10.

N.C.J. Strynadka, Mark Paetzel, Franck Danel, +3

Nature Structural Biology

Crystal StructureBiochemistryProtein X-ray CrystallographyStructure ElucidationCrystallography +1

Structural Insights into the Anti-methicillin-resistant Staphylococcus aureus (MRSA) Activity of Ceftobiprole

Andrew L. Lovering, Michael Gretes, Susan S. Safadi, +4

Journal of Biological Chemistry

OXA-17, a Further Extended-Spectrum Variant of OXA-10 β-Lactamase, Isolated from <i>Pseudomonas aeruginosa</i>

Franck Danel, Lucinda M. C. Hall, Brigid Duke, +2

Antimicrobial Agents and Chemotherapy

Ceftazidime ResistanceBacteriologyAntibiotic ResistanceBacterial PathogensOxa-10 β-Lactamase +18

OXA-14, another extended-spectrum variant of OXA-10 (PSE-2) beta-lactamase from Pseudomonas aeruginosa

Franck Danel, Lucinda M. C. Hall, Deniz Gür, +1

Antimicrobial Agents and Chemotherapy

Position 143Antimicrobial Resistance GeneHealth SciencesBiochemistryAntibiotics +11

OXA-15, an extended-spectrum variant of OXA-2 beta-lactamase, isolated from a Pseudomonas aeruginosa strain

Franck Danel, Linda M. Hall, Deniz Gür, +1

Antimicrobial Agents and Chemotherapy

Pseudomonas Aeruginosa AhBacteriologyEscherichia ColiAntibiotic ResistanceDrug Resistance +17

OXA-16, a Further Extended-Spectrum Variant of OXA-10 β-Lactamase, from Two <i>Pseudomonas aeruginosa</i> Isolates

Franck Danel, Lucinda M. C. Hall, Deniz Gür, +1

Antimicrobial Agents and Chemotherapy

Pseudomonas Aeruginosa IsolatesBacteriologyAntibiotic ResistanceBacterial PathogensOxa-10 β-Lactamase +14

The structure and function of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Haemophilus influenzae 1 1Edited by R. Huber

Michael Hennig, Glenn E. Dale, A. D’Arcy, +8

Journal of Molecular Biology

Natural SciencesMolecular BiologyR. HuberMicrobiologyChemical Biology +3

Discovering New Classes of Brugia malayi Asparaginyl-tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change

Sai Chetan K. Sukuru, Thibaut Crépin, Youli Milev, +13

Journal of Computer-Aided Molecular Design

Medicinal ChemistryBiosynthesisBioorganic ChemistryRelating SpecificityBiochemistry +11