William C. Forrester

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

Guangchao Sui, Christina Soohoo, El Bachir Affar et al. · Proceedings of the National Academy of Sciences · 2002 · 1.1K citations · Full text

Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

Eric S. Fischer, Kerstin Böhm, John R. Lydeard et al. · Nature · 2014 · 1K citations · Full text

p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells

Robert J. Ihry, Kathleen A. Worringer, Max R. Salick et al. · Nature Medicine · 2018 · 988 citations

Medicine, Stem Cell Engineering, Stem Cells +8

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 687 citations · Full text

Bioinformatics, Tumor Biology, Radiation Oncology +13

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

William C. Forrester, Elliot Epner, Monica Driscoll et al. · Genes & Development · 1990 · 473 citations · Full text

Genetics, Genomic Mechanism, Molecular Genetics +18