Lorin Crawford

Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

Srivatsan Raghavan, Peter Winter, Andrew W. Navia et al. · Cell · 2021 · 537 citations · Full text

Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits

Lorin Crawford, Ping Zeng, Sayan Mukherjee et al. · PLoS Genetics · 2017 · 129 citations · Full text

Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity

Ryan S. Soderquist, Lorin Crawford, Esther Liu et al. · Nature Communications · 2018 · 116 citations · Full text

Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence

Katherine R. Singleton, Lorin Crawford, Elizabeth Tsui et al. · Cell Reports · 2017 · 106 citations · Full text

Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Kevin Lin, Justine C. Rutter, Abigail Xie et al. · Nature Genetics · 2020 · 89 citations

Drug Target, Health Sciences, Drug Design +12