Abigail Xie

Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

Sydney X. Lu, Emma De Neef, James D. Thomas et al. · Cell · 2021 · 267 citations · Full text

Immunology, Rna Splicing, Tumor Immunity +6

Targeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia

Kevin Lin, Peter Winter, Abigail Xie et al. · Scientific Reports · 2016 · 173 citations · Full text

Hematological Malignancy, Tumor Biology, Selective Small-molecule Antagonist +14

Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity

Kevin Lin, Abigail Xie, Justine C. Rutter et al. · Cell Metabolism · 2019 · 109 citations · Full text

Biochemistry, Drug Sensitivity, Medicine +10

Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Kevin Lin, Justine C. Rutter, Abigail Xie et al. · Nature Genetics · 2020 · 89 citations

Drug Target, Health Sciences, Drug Design +12

P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia

Kevin Lin, Justine C. Rutter, Abigail Xie et al. · Nature Cancer · 2022 · 38 citations · Full text

Hematological Malignancy, Medicine, Acute Myeloid Leukemia +9