Katherine R. Singleton

A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop

K E Ware, Trista K. Hinz, Emily K. Kleczko et al. · Oncogenesis · 2013 · 255 citations · Full text

Systematic identification of signaling pathways with potential to confer anticancer drug resistance

Colin A. Martz, Kathleen Ottina, Katherine R. Singleton et al. · Science Signaling · 2014 · 197 citations · Full text

Drug Target, Breast Oncology, Cancer Biology +23

Fibroblast Growth Factor Receptors Are Components of Autocrine Signaling Networks in Head and Neck Squamous Cell Carcinoma Cells

Marianne E. Marshall, Trista K. Hinz, Scott A. Kono et al. · Clinical Cancer Research · 2011 · 106 citations · Full text

Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence

Katherine R. Singleton, Lorin Crawford, Elizabeth Tsui et al. · Cell Reports · 2017 · 106 citations · Full text

Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Kevin Lin, Justine C. Rutter, Abigail Xie et al. · Nature Genetics · 2020 · 89 citations

Drug Target, Health Sciences, Drug Design +12