Ryan S. Soderquist

Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity

Ryan S. Soderquist, Lorin Crawford, Esther Liu et al. · Nature Communications · 2018 · 116 citations · Full text

Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity

Kevin Lin, Abigail Xie, Justine C. Rutter et al. · Cell Metabolism · 2019 · 109 citations · Full text

Biochemistry, Drug Sensitivity, Medicine +10

Multiple BH3 Mimetics Antagonize Antiapoptotic MCL1 Protein by Inducing the Endoplasmic Reticulum Stress Response and Up-regulating BH3-only Protein NOXA

Tina C. Albershardt, Bethany L. Salerni, Ryan S. Soderquist et al. · Journal of Biological Chemistry · 2011 · 104 citations · Full text

Reductive Stress, Hematological Malignancy, Protein Function +14

Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication

Behailu Birhanu Aklilu, Ryan S. Soderquist, Kevin M. Culligan · Nucleic Acids Research · 2013 · 90 citations · Full text

A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution

Grace R. Anderson, Peter Winter, Kevin Lin et al. · Cell Reports · 2017 · 85 citations · Full text

Therapeutic Cooperativity, Combinatorial Inhibition, Oncology +15