Shyla George

Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease

Shyla George, Marco F. Schmidt, Samer Al‐Gharabli et al. · Antiviral Research · 2011 · 127 citations · Full text

Sars-coronavirus Main Protease, Biochemistry, Peptide Library +6

3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses

Jinzhi Tan, Shyla George, Yuri Kusov et al. · Journal of Virology · 2013 · 116 citations · Full text

Crystal Structure, Cleavage Specificity, Viral Polymerase Structure +19

Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68

Liang Sun, Adam Meijer, Linlin Zhang et al. · Antimicrobial Agents and Chemotherapy · 2015 · 78 citations · Full text

The Enterovirus 3C Protease Inhibitor SG85 Efficiently Blocks Rhinovirus Replication and Is Not Cross-Resistant with Rupintrivir

Céline Lacroix, Shyla George, Pieter Leyssen et al. · Antimicrobial Agents and Chemotherapy · 2015 · 26 citations · Full text

Viral Replication, Molecular Virology, Viral Polymerase Structure +15

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases

Lonneke van der Linden, Rachel Ulferts, Sander B. Nabuurs et al. · Antiviral Research · 2014 · 20 citations · Full text

Diagnostic Virology, Molecular Virology, Biochemistry +14