Concepedia

Author

Pieter Leyssen

Rega Institute for Medical ResearchORCID

Also Known As

Laitinen, Tuomo, Leyssen, P., Leyssen, Pieter, P LEYSSEN, P Leyssen, P. Leyssen, Pieter Leyssen, Sharma, Sujata

282

Publications

9.9K

Citations

53

H-Index

88

Concepts

All Affiliations

Rega Institute for Medical ResearchKU LeuvenCentre National de la Recherche ScientifiqueInstitut de Chimie des Substances NaturellesAix-Marseille Université
PL

About

Pieter Leyssen is an author at Rega Institute for Medical Research specializing in medicine, virology, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

39

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3.9K

2

Natural Sciences

20

24

1.5K

3

Biochemistry

17

20

1.2K

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Engineering

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Health Sciences

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70

Pieter Leyssen

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155

Publications

9.2K

Citations

51

H-Index

YearCitations

α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment

Linlin Zhang, Daizong Lin, Yuri Kusov,

Journal of Medicinal Chemistry

2020

593

Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern

Laura Vangeel, Winston Chiu, Steven De Jonghe,

Antiviral Research

2022

424

Bioactivity-Based Molecular Networking for the Discovery of Drug Leads in Natural Product Bioassay-Guided Fractionation

Louis‐Félix Nothias, Mélissa Nothias-Esposito, Ricardo Silva,

Journal of Natural Products

2018

388

The Predominant Mechanism by Which Ribavirin Exerts Its Antiviral Activity In Vitro against Flaviviruses and Paramyxoviruses Is Mediated by Inhibition of IMP Dehydrogenase

Pieter Leyssen, Jan Balzarini, Erik De Clercq,

Journal of Virology

2005

290

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne J. F. Kaptein,

Nature Communications

2020

287

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein

Jeroen R. P. M. Strating, Lonneke van der Linden, Lucian Albulescu,

Cell Reports

2015

247

Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral

Leen Delang, Nidya Alexandra Segura Guerrero, Ali Taş,

Journal of Antimicrobial Chemotherapy

2014

225

Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen

Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen,

ACS Pharmacology & Translational Science

2021

154

The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model

Rana Abdelnabi, Caroline S. Foo, Suzanne J. F. Kaptein,

EBioMedicine

2021

142

Favipiravir (T-705) inhibits in vitro norovirus replication

Joana Rocha‐Pereira, Dirk Jochmans, Kai Dallmeier,

Biochemical and Biophysical Research Communications

2012

135

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