Steven De Jonghe

Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern

Laura Vangeel, Winston Chiu, Steven De Jonghe et al. · Antiviral Research · 2022 · 424 citations · Full text

Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov et al. · Journal of the American Chemical Society · 2022 · 234 citations · Full text

Viral Diagnostics, Immunology, Molecular Biology +18

Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects

Elena Bekerman, Grégory Neveu, Ana Shulla et al. · Journal of Clinical Investigation · 2017 · 230 citations · Full text

Hcv Particles, Medicine, Global Health +15

The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor <i>In Vitro</i> and Confer Resistance To Nirmatrelvir

Dirk Jochmans, Kim Donckers, Antitsa Stoycheva et al. · mBio · 2023 · 163 citations · Full text

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

Melissa L. Boby, D. Fearon, Matteo P. Ferla et al. · Science · 2023 · 158 citations · Full text