Steven De Jonghe

Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern

Laura Vangeel, Winston Chiu, Steven De Jonghe et al. · Antiviral Research · 2022 · 433 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +17

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Jitske Jansen, Katharina C. Reimer, James S. Nagai et al. · Cell stem cell · 2021 · 266 citations · Full text

Medicine, Infectious Diseases, Pathology +17

Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov et al. · Journal of the American Chemical Society · 2022 · 244 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects

Elena Bekerman, Grégory Neveu, Ana Shulla et al. · Journal of Clinical Investigation · 2017 · 237 citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor <i>In Vitro</i> and Confer Resistance To Nirmatrelvir

Dirk Jochmans, Kim Donckers, Antitsa Stoycheva et al. · mBio · 2023 · 170 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +16