Linlin Zhang

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

Linlin Zhang, Daizong Lin, Xinyuanyuan Sun et al. · Science · 2020 · 3.4K citations · Full text

α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment

Linlin Zhang, Daizong Lin, Yuri Kusov et al. · Journal of Medicinal Chemistry · 2020 · 593 citations · Full text

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

Jian Lei, Guido Hansen, Christoph Nitsche et al. · Science · 2016 · 365 citations

Virus Structure, Crystal Structure, Biochemistry +14

SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging

Wioletta Rut, Katarzyna Groborz, Linlin Zhang et al. · Nature Chemical Biology · 2020 · 321 citations · Full text

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

Jan Wenzel, Josephine Lampe, Helge Müller‐Fielitz et al. · Nature Neuroscience · 2021 · 257 citations · Full text