Concepedia

Jian Lei

JL

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Publications

27

Citations

1.9K

H-Index

19

Active since

2005

Affiliations

Sichuan University(Current)

German Center for Infection Research

University of Lübeck

State Key Laboratory of Biotherapy

Chinese Academy of Sciences

Jian Lei is an author at Sichuan University specializing in life sciences, structural biology, and molecular virology.

ORCID

Publications per year

2005–2024

27

Publications

27

SARS-CoV-2 M <sup>pro</sup> inhibitors with antiviral activity in a transgenic mouse model

Jingxin Qiao, Yueshan Li, Rui Zeng et al. · Science · 2021 · 450 citations · Full text

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Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

Jian Lei, Guido Hansen, Christoph Nitsche et al. · Science · 2016 · 378 citations · Full text

, , +17

p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PL <sup>pro</sup> via E3 ubiquitin ligase RCHY1

Yue Ma‐Lauer, Javier Carbajo-Lozoya, Marco Y. Hein et al. · Proceedings of the National Academy of Sciences · 2016 · 214 citations · Full text

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Structural characterization of the C-terminal domain of SARS-CoV-2 nucleocapsid protein

Renjie Zhou, Rui Zeng, Albrecht von Brunn et al. · Molecular Biomedicine · 2020 · 121 citations · Full text

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An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron

Baoxue Quan, Huiping Shuai, Anjie Xia et al. · Nature Microbiology · 2022 · 101 citations · Full text

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