Marco F. Schmidt

Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease

Shyla George, Marco F. Schmidt, Samer Al‐Gharabli et al. · Antiviral Research · 2011 · 128 citations · Full text

Life Sciences, Biochemistry, Infectious Diseases +16

Sensitized Detection of Inhibitory Fragments and Iterative Development of Non‐Peptidic Protease Inhibitors by Dynamic Ligation Screening

Marco F. Schmidt, Albert Isidro‐Llobet, Michael Lisurek et al. · Angewandte Chemie International Edition · 2008 · 72 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

An Efficient Method for the Synthesis of Peptide Aldehyde Libraries Employed in the Discovery of Reversible SARS Coronavirus Main Protease (SARS‐CoV M^pro) Inhibitors

Samer Al‐Gharabli, Syed Tasadaque Ali Shah, Steffen Weik et al. · ChemBioChem · 2006 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design, Synthesis, and Qualitative Structure–Activity Evaluations of Novel β-Secretase Inhibitors as Potential Alzheimer’s Drug Leads

Taleb H. Al‐Tel, Mohammad H. Semreen, Raed A. Al‐Qawasmeh et al. · Journal of Medicinal Chemistry · 2011 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Selective Identification of Cooperatively Binding Fragments in a High‐Throughput Ligation Assay Enables Development of a Picomolar Caspase‐3 Inhibitor

Marco F. Schmidt, Adeeb El‐Dahshan, Sandro Keller et al. · Angewandte Chemie International Edition · 2009 · 50 citations

Life Sciences, Biochemistry, Molecular Biology +13