Bruno Simoneau

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

Daniel Lamarre, Paul C. Anderson, Murray D. Bailey et al. · Nature · 2003 · 911 citations

Antiviral Effects, Hepatology, Hepatitis C Virus +9

Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease

James J. Crute, Christine A. Grygon, Karl D. Hargrave et al. · Nature Medicine · 2002 · 230 citations

Molecular Virology, Viral Persistence, Pathogenesis +7

Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1

Lee D. Fader, Éric Malenfant, Mathieu Parisien et al. · ACS Medicinal Chemistry Letters · 2014 · 175 citations · Full text

Hiv-1 Integrase, Immunology, Molecular Biology +16

Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase

Michel Liuzzi, Stephen W. Mason, Mireille Cartier et al. · Journal of Virology · 2005 · 129 citations · Full text

Viral Replication, Molecular Virology, Neurovirology +13

Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein

Christopher T. Lemke, Steve Titolo, Uta von Schwedler et al. · Journal of Virology · 2012 · 124 citations · Full text