Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease

James J. Crute, Christine A. Grygon, Karl D. Hargrave, +6

Nature Medicine

Molecular VirologyViral PersistencePathogenesisViral PathogenesisHuman Disease +5

Synthesis and Biological Evaluation of Aryl-phospho-indole as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

François-René Alexandre, Agnès Amador, Stéphanie Bot, +12

Journal of Medicinal Chemistry

Medicinal ChemistryWild-type Hiv-1BiochemistryMedicineNatural Sciences +11

Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication

Frédéric H. Vaillancourt, Louise Pilote, Mireille Cartier, +5

Virology

Lipid KinaseViral ReplicationMolecular VirologyHost FactorViral Hepatitis +8

A potent peptidomimetic inhibitor of HSV ribonucleotide reductase with antiviral activity in vivo

Michel Liuzzi, Robert Déziel, Nell Moss, +11

Nature

Molecular VirologyAntiviral AgentsAntiviral ActivityMedicineAntiviral Drug Development +10

Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase

Michel Liuzzi, Stephen W. Mason, Mireille Cartier, +17

Journal of Virology

Viral ReplicationMolecular VirologyNeurovirologyMedicineNatural Sciences +11

A new approach to the study of the base-excision repair pathway using methoxyamine.

Michel Liuzzi, Myriam Talpaert-Borlè

Journal of Biological Chemistry

Reaction of apurinic/apyrimidinic sites with [14C]methoxyamine

Myriam Talpaert-Borl≐, Michel Liuzzi

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

BiochemistryNatural SciencesMechanism Of ActionChemical BiologyPharmacology +1

Interaction between Human Respiratory Syncytial Virus (RSV) M2-1 and P Proteins Is Required for Reconstitution of M2-1-Dependent RSV Minigenome Activity

Stephen W. Mason, Erika Aberg, Carol Lawetz, +3

Journal of Virology

P ProteinsViral ReplicationMolecular VirologyMedicineNatural Sciences +11

Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor

Cyril B. Dousson, François-René Alexandre, Agnès Amador, +24

Journal of Medicinal Chemistry

Medicinal ChemistryDrug Resistant VirusMedicineNatural SciencesAntiviral Drug Development +11

Discovery and characterization of a novel 7-aminopyrazolo[1,5-a]pyrimidine analog as a potent hepatitis C virus inhibitor

Jong Yeon Hwang, Marc P. Windisch, Suyeon Jo, +18

Bioorganic & Medicinal Chemistry Letters

BiochemistryMedicineAntiviral Drug DevelopmentAntiviral TherapyHepatitis +4