Stéphanie Bot

Synthesis and Biological Evaluation of Aryl-phospho-indole as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

François-René Alexandre, Agnès Amador, Stéphanie Bot et al. · Journal of Medicinal Chemistry · 2010 · 177 citations

Medicinal Chemistry, Wild-type Hiv-1, Biochemistry +13

Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor

Cyril B. Dousson, François-René Alexandre, Agnès Amador et al. · Journal of Medicinal Chemistry · 2016 · 72 citations

Medicinal Chemistry, Drug Resistant Virus, Medicine +13

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors

François-René Alexandre, Eric Badaroux, John P. Bilello et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 32 citations · Full text

Medicine, Antiviral Drug Development, Antiviral Therapy +9

Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor

Jean‐Laurent Paparin, Agnès Amador, Eric Badaroux et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 11 citations

Development and Scale-Up of a Manufacturing Route for the Non-nucleoside Reverse Transcriptase Inhibitor GSK2248761A (IDX-899): Synthesis of an Advanced Key Chiral Intermediate

Richard K. Bellingham, Gary T. Borrett, Guillaume Bret et al. · Organic Process Research & Development · 2018 · 10 citations

Manufacturing Route, Engineering, Phosphinate Ester Gsk2248761a +15