Jean‐Laurent Paparin

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors

François-René Alexandre, Eric Badaroux, John P. Bilello et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 32 citations · Full text

Medicine, Antiviral Drug Development, Antiviral Therapy +9

Synthesis and Functionalization of New Tropanes Designed for Use as Scaffolds in Combinatorial Chemistry

Jean‐Laurent Paparin, Christophe Crévisy, René Grée · European Journal of Organic Chemistry · 2000 · 26 citations

Combinatorial Chemistry, Diversity Oriented Synthesis, Supramolecular Assembly +15

Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase

Claire Pierra Rouvière, Agnès Amador, Eric Badaroux et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 12 citations · Full text

Viral Polymerase, Medicine, Drug Discovery +8

Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor

Jean‐Laurent Paparin, Agnès Amador, Eric Badaroux et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 11 citations

tert-Butoxycarbamate group: a useful protecting group for the synthesis of orthogonally protected ‘tropane-like’ scaffolds

Jean‐Laurent Paparin, Christophe Crévisy, René Grée · Tetrahedron Letters · 2000 · 10 citations

Engineering, Natural Sciences, Useful Protecting Group +7