Eric Badaroux

588 IN VITRO ANTIVIRAL ACTIVITY AND PHARMACOLOGY OF IDX184, A NOVEL AND POTENT INHIBITOR OF HCV REPLICATION

E. Cretton‐Scott, Christian Périgaud, Suzanne Peyrottes et al. · Journal of Hepatology · 2008 · 33 citations

Neurovirology, Viral Polymerase Mechanism, Immunology +7

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors

François-René Alexandre, Eric Badaroux, John P. Bilello et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 32 citations · Full text

Medicine, Antiviral Drug Development, Antiviral Therapy +9

Synthesis of 2'-C-Methylcytidine and 2'-C-Methyluridine Derivatives Modified in the 3'-Position as Potential Antiviral Agents

Claire Pierra, Agnès Amador, Eric Badaroux et al. · Collection of Czechoslovak Chemical Communications · 2006 · 19 citations

2'-C-methyluridine Derivatives, Bioorganic Chemistry, Synthetic Virology +19

Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase

Claire Pierra Rouvière, Agnès Amador, Eric Badaroux et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 12 citations · Full text

Viral Polymerase, Medicine, Drug Discovery +8

Design, Synthesis and Antiviral Evaluation of 2′- <i>C</i> -Methyl Branched Guanosine Pronucleotides: The Discovery of IDX184, a Potent Liver-Targeted HCV Polymerase Inhibitor

Gwenaëlle Sizun, Claire Pierra, Jérôme Peyronnet et al. · Future Medicinal Chemistry · 2015 · 11 citations