Frédéric H. Vaillancourt

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

Leah C. Blasiak, Frédéric H. Vaillancourt, Christopher T. Walsh et al. · Nature · 2006 · 392 citations

Crystal Structure, Biosynthesis, Biochemistry +7

SyrB2 in syringomycin E biosynthesis is a nonheme Fe ^II α-ketoglutarate- and O ₂ -dependent halogenase

Frédéric H. Vaillancourt, Jun Yin, Christopher T. Walsh · Proceedings of the National Academy of Sciences · 2005 · 329 citations · Full text

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

Frédéric H. Vaillancourt, Ellen Yeh, David A. Vosburg et al. · Nature · 2005 · 318 citations

Biosynthesis, Bioorganic Chemistry, Engineering +10

Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2

Megan L. Matthews, Courtney M. Krest, Eric W. Barr et al. · Biochemistry · 2009 · 247 citations · Full text

Halogenation, Biosynthesis, Bioorganic Chemistry +15

Halogenation of Unactivated Carbon Centers in Natural Product Biosynthesis:  Trichlorination of Leucine during Barbamide Biosynthesis

Danica P. Galonić, Frédéric H. Vaillancourt, Christopher T. Walsh · Journal of the American Chemical Society · 2006 · 188 citations

Engineering, Molecular Biology, Barbamide Biosynthesis +19