Frédéric H. Vaillancourt

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

Leah C. Blasiak, Frédéric H. Vaillancourt, Christopher T. Walsh et al. · Nature · 2006 · 398 citations

Life Sciences, Biochemistry, Microbiology +9

SyrB2 in syringomycin E biosynthesis is a nonheme Fe ^II α-ketoglutarate- and O ₂ -dependent halogenase

Frédéric H. Vaillancourt, Jun Yin, Christopher T. Walsh · Proceedings of the National Academy of Sciences · 2005 · 334 citations · Full text

Life Sciences, Biochemistry, Microbiology +15

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

Frédéric H. Vaillancourt, Ellen Yeh, David A. Vosburg et al. · Nature · 2005 · 321 citations

Life Sciences, Biochemistry, Molecular Biology +10

Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2

Megan L. Matthews, Courtney M. Krest, Eric W. Barr et al. · Biochemistry · 2009 · 252 citations · Full text

Pharmacy, Biochemistry, Chemistry +15

Halogenation of Unactivated Carbon Centers in Natural Product Biosynthesis:  Trichlorination of Leucine during Barbamide Biosynthesis

Danica P. Galonić, Frédéric H. Vaillancourt, Christopher T. Walsh · Journal of the American Chemical Society · 2006 · 192 citations

Life Sciences, Biochemistry, Molecular Biology +13