Megan L. Matthews

Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2

Megan L. Matthews, Christopher S. Neumann, Linde A. Miles et al. · Proceedings of the National Academy of Sciences · 2009 · 257 citations · Full text

Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2

Shaun D. Wong, Martin Srnec, Megan L. Matthews et al. · Nature · 2013 · 252 citations · Full text

Aldehyde Dehydrogenase, Biochemistry, Natural Sciences +8

Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2

Megan L. Matthews, Courtney M. Krest, Eric W. Barr et al. · Biochemistry · 2009 · 247 citations · Full text

Halogenation, Biosynthesis, Bioorganic Chemistry +15

Enterococci enhance Clostridioides difficile pathogenesis

Alexander B. Smith, Matthew L. Jenior, Orlaith Keenan et al. · Nature · 2022 · 207 citations · Full text

Microbial Disease, Antimicrobial Susceptibility, Virulence Factor +5

Highly Selective Inhibitors of Monoacylglycerol Lipase Bearing a Reactive Group that Is Bioisosteric with Endocannabinoid Substrates

Jae Won Chang, Micah J. Niphakis, Kenneth M. Lum et al. · Chemistry & Biology · 2012 · 188 citations · Full text

Chemical Biology, Endocannabinoid Substrates, Lipid Synthesis +8