Kenneth M. Lum

Proteome-wide covalent ligand discovery in native biological systems

Keriann M. Backus, Bruno E. Correia, Kenneth M. Lum et al. · Nature · 2016 · 936 citations

Biochemistry, Natural Sciences, Proteomics +3

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

Ekaterina V. Vinogradova, Xiaoyu Zhang, David Remillard et al. · Cell · 2020 · 352 citations · Full text

Electrophile-cysteine Interactions, Signal Transduction, Biochemistry +10

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

Micah J. Niphakis, Kenneth M. Lum, Armand B. Cognetta et al. · Cell · 2015 · 243 citations · Full text

Proteinlipid Interaction, Signal Transduction, Their Ligandability +12

Highly Selective Inhibitors of Monoacylglycerol Lipase Bearing a Reactive Group that Is Bioisosteric with Endocannabinoid Substrates

Jae Won Chang, Micah J. Niphakis, Kenneth M. Lum et al. · Chemistry & Biology · 2012 · 188 citations · Full text

Chemical Biology, Endocannabinoid Substrates, Lipid Synthesis +8

ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth

Jarrett R. Remsberg, Radu M. Suciu, Noemi A. Zambetti et al. · Nature Chemical Biology · 2021 · 127 citations · Full text

Cell Signaling, Medicine, Pathology +9