Kimberly G. Petrov

Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors

Tara Rheault, John Stellwagen, George M. Adjabeng et al. · ACS Medicinal Chemistry Letters · 2013 · 253 citations · Full text

B-raf-driven Tumors, Antitumor Activity, Hyperactive Signaling +16

Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series

Kimberly G. Petrov, Yuemei Zhang, Malcolm Carter et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 162 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +11

Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles

Edgar R. Wood, Lee F. Kuyper, Kimberly G. Petrov et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 131 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +10

6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases

Edgar R. Wood, Lisa M. Shewchuk, Byron Ellis et al. · Proceedings of the National Academy of Sciences · 2008 · 110 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +13

Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors

Tara Rheault, Thomas R. Caferro, Scott H. Dickerson et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 83 citations · Full text

Medicinal Chemistry, Medicine, Pharmacotherapy +5