Nicholas J. Panzarino

Replication fork stability confers chemoresistance in BRCA-deficient cells

Arnab Ray Chaudhuri, Elsa Callén, Xia Ding et al. · Nature · 2016 · 904 citations · Full text

Brca-deficient Cells, Genome Instability, Natural Sciences +5

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency

Ke Cong, Min Peng, Arne Nedergaard Kousholt et al. · Molecular Cell · 2021 · 298 citations · Full text

Genome Instability, Natural Sciences, Key Determinant +8

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress

Min Peng, Ke Cong, Nicholas J. Panzarino et al. · Cell Reports · 2018 · 73 citations · Full text

PARPi synthetic lethality derives from replication-associated single-stranded DNA gaps

Ke Cong, Arne Nedergaard Kousholt, Min Peng et al. · 2019 · 21 citations · Full text

Chromatin, Genome Instability, Dna Damage +11

Replication gaps underlie BRCA-deficiency and therapy response

Nicholas J. Panzarino, John J. Krais, Min Peng et al. · 2019 · 14 citations · Full text