Bonnie Liu

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou, Kyung Song, Ivana Yen et al. · Nature · 2010 · 1.6K citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Mapk Pathway +8

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

Anneleen Daemen, David Peterson, Nisebita Sahu et al. · Proceedings of the National Academy of Sciences · 2015 · 403 citations · Full text

Metabolomic Profiling, Pathology, Metabolic Remodeling +24

A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types

Marie-Claire Wagle, Daniel C. Kirouac, Christiaan Klijn et al. · npj Precision Oncology · 2018 · 210 citations · Full text

ERK Inhibition Overcomes Acquired Resistance to MEK Inhibitors

Georgia Hatzivassiliou, Bonnie Liu, Carol O’Brien et al. · Molecular Cancer Therapeutics · 2012 · 208 citations · Full text

Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State

Anneleen Daemen, Bonnie Liu, Kyung Song et al. · Cell Metabolism · 2018 · 92 citations · Full text

Pan-cancer Metabolic Signature, Biochemistry, Oncogenic Agent +10