Marie-Claire Wagle

R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism

Kyung-Ah Kim, Marie-Claire Wagle, Karolyn Tran et al. · Molecular Biology of the Cell · 2008 · 348 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

Minke E. Binnerts, Kyung-Ah Kim, Jessica Bright et al. · Proceedings of the National Academy of Sciences · 2007 · 284 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types

Marie-Claire Wagle, Daniel C. Kirouac, Christiaan Klijn et al. · npj Precision Oncology · 2018 · 213 citations · Full text

Medicine, Cancer Biology, Oncology +17

R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/β-catenin pathway

Jingsong Zhao, Kyung‐Ah Kim, Josephine De Vera et al. · Proceedings of the National Academy of Sciences · 2009 · 113 citations · Full text

Medicine, Oncology, Radiation Oncology +17

Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors

Mark Merchant, John G. Moffat, Gabriele Schaefer et al. · PLoS ONE · 2017 · 93 citations · Full text

Medicine, Cancer Biology, Oncology +17