Marie-Claire Wagle

R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism

Kyung-Ah Kim, Marie-Claire Wagle, Karolyn Tran et al. · Molecular Biology of the Cell · 2008 · 344 citations · Full text

Wnt Amplification, Molecular Regulation, Common Mechanism +20

R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

Minke E. Binnerts, Kyung-Ah Kim, Jessica Bright et al. · Proceedings of the National Academy of Sciences · 2007 · 282 citations · Full text

A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types

Marie-Claire Wagle, Daniel C. Kirouac, Christiaan Klijn et al. · npj Precision Oncology · 2018 · 210 citations · Full text

R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/β-catenin pathway

Jingsong Zhao, Kyung‐Ah Kim, Josephine De Vera et al. · Proceedings of the National Academy of Sciences · 2009 · 112 citations · Full text

Tongue Ulceration, Immunology, Pathology +19

Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors

Mark Merchant, John G. Moffat, Gabriele Schaefer et al. · PLoS ONE · 2017 · 90 citations · Full text

Erk Inhibition, Cancer Biology, Braf Mutant Models +16