Bassem D. Khalil

G Protein–Coupled Receptor–Mediated Activation of p110β by Gβγ Is Required for Cellular Transformation and Invasiveness

Hashem A. Dbouk, Oscar Vadas, Aliaksei Shymanets et al. · Science Signaling · 2012 · 146 citations · Full text

Molecular Biology, Cellular Physiology, Tumor Biology +23

Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs)

Oscar Vadas, Hashem A. Dbouk, Aliaksei Shymanets et al. · Proceedings of the National Academy of Sciences · 2013 · 136 citations · Full text

P101 Subunits, Molecular Pharmacology, Signaling Pathway +20

An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy

Bassem D. Khalil, Roberto Sánchez, Tasrina Rahman et al. · The Journal of Experimental Medicine · 2021 · 96 citations · Full text

Tumor Biology, Systems Biology, Nuclear Receptor Nr2f1 +13

GPCR Signaling Mediates Tumor Metastasis via PI3Kβ

Bassem D. Khalil, Christine Hsueh, Yanyan Cao et al. · Cancer Research · 2016 · 52 citations · Full text

Characterization of a Tumor-Associated Activating Mutation of the p110β PI 3-Kinase

Hashem A. Dbouk, Bassem D. Khalil, Haiyan Wu et al. · PLoS ONE · 2013 · 51 citations · Full text

Pi3-kinase Pathway, Molecular Biology, Tumor-associated Activating Mutation +22