Marc Hattenberger

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 701 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

A rat model of bone cancer pain

Stephen J. Medhurst, Katherine Walker, M. Bowes et al. · Pain · 2002 · 307 citations

Medicine, Cancer Biology, Bone Metabolism +15

Identifying Optimal Biologic Doses of Everolimus (RAD001) in Patients With Cancer Based on the Modeling of Preclinical and Clinical Pharmacokinetic and Pharmacodynamic Data

Chiaki Tanaka, Terence O’Reilly, John M. Kovarik et al. · Journal of Clinical Oncology · 2008 · 210 citations

Medicine, Pharmacokinetics, Pharmacology +17

Characterization of the Mechanism of Action of the Pan Class I PI3K Inhibitor NVP-BKM120 across a Broad Range of Concentrations

Saskia M. Brachmann, Julia Kleylein-Sohn, Swann Gaulis et al. · Molecular Cancer Therapeutics · 2012 · 120 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers

Stéphane Ferretti, Jacques Hamon, Ruben de Kanter et al. · Nature · 2024 · 113 citations · Full text

Life Sciences, Oncology, Pharmacology +17