Saskia M. Brachmann

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent <i>in vivo</i> antitumor activity

Sauveur-Michel Maira, Frédéric Stauffer, Josef Brueggen et al. · Molecular Cancer Therapeutics · 2008 · 1.1K citations · Full text

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 687 citations · Full text

Bioinformatics, Tumor Biology, Radiation Oncology +13

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

Otília V. Vieira, Roberto J. Botelho, Lucia E. Rameh et al. · The Journal of Cell Biology · 2001 · 524 citations · Full text

Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor

Sauveur-Michel Maira, Sabina Pecchi, Alan Huang et al. · Molecular Cancer Therapeutics · 2011 · 524 citations

Pharmacotherapy, Different Selectivity Profile, Chemical Biology +26

Breast Cancer–Associated <i>PIK3CA</i> Mutations Are Oncogenic in Mammary Epithelial Cells

Steven J. Isakoff, Jeffrey A. Engelman, Hanna Y. Irie et al. · Cancer Research · 2005 · 490 citations