Gary J. Jenkins

Relationship between amorphous solid dispersion in vivo absorption and in vitro dissolution: phase behavior during dissolution, speciation, and membrane mass transport

Venecia R. Wilson, Xiaochun Lou, Donald J. Osterling et al. · Journal of Controlled Release · 2018 · 153 citations

Membrane Mass Transport, Diffusion Resistance, Transport Phenomena +6

Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity

Milan Bruncko, Le Wang, George S. Sheppard et al. · Journal of Medicinal Chemistry · 2015 · 150 citations · Full text

Drug Target, Mcl-1 Inhibitors, High Throughput +23

The Hsp90 Cochaperone p23 Is the Limiting Component of the Multiprotein Hsp90/Hsp70-based Chaperone System in Vivo Where It Acts to Stabilize the Client Protein·Hsp90 Complex

Yoshihiro Morishima, Kimon C. Kanelakis, Patrick J. Murphy et al. · Journal of Biological Chemistry · 2003 · 96 citations · Full text

Molecular Biology, Sf9 Cells, Molecular Research +20

Towards in vitro models for reducing or replacing the use of animals in drug testing

David M. Stresser, Anna K. Kopec, Philip Hewitt et al. · Nature Biomedical Engineering · 2023 · 75 citations

Animal Testing, Xenotransplantation, Preclinical Drug Evaluation +11

Ubiquitylation of Neuronal Nitric-oxide Synthase by CHIP, a Chaperone-dependent E3 Ligase

Hwei‐Ming Peng, Yoshihiro Morishima, Gary J. Jenkins et al. · Journal of Biological Chemistry · 2004 · 71 citations · Full text