Anna K. Kopec

Thrombin promotes diet-induced obesity through fibrin-driven inflammation

Anna K. Kopec, Sara R. Abrahams, Sherry Thornton et al. · Journal of Clinical Investigation · 2017 · 115 citations · Full text

Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium

Chad M. Thompson, Deborah M. Proctor, Laurie C. Haws et al. · Toxicological Sciences · 2011 · 92 citations · Full text

Pathology, Cancer Biology, Toxicological Mechanism +18

Thrombin Inhibition with Dabigatran Protects against High-Fat Diet–Induced Fatty Liver Disease in Mice

Anna K. Kopec, Nikita Joshi, Keara Towery et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 79 citations · Full text

Fibrin(ogen) drives repair after acetaminophen-induced liver injury via leukocyte αMβ2 integrin-dependent upregulation of Mmp12

Anna K. Kopec, Nikita Joshi, Holly Cline-Fedewa et al. · Journal of Hepatology · 2016 · 78 citations · Full text

Inflammation, Fibrosis, Liver Physiology +11

Towards in vitro models for reducing or replacing the use of animals in drug testing

David M. Stresser, Anna K. Kopec, Philip Hewitt et al. · Nature Biomedical Engineering · 2023 · 75 citations

Animal Testing, Xenotransplantation, Preclinical Drug Evaluation +11