Concepedia

Towards in vitro models for reducing or replacing the use of animals in drug testing

David M. Stresser, Anna K. Kopec, Philip Hewitt, Rhiannon N. Hardwick, Terry R. Van Vleet, Prathap Kumar S. Mahalingaiah, D OCONNELL, Gary J. Jenkins, Rhiannon David, Jessica Graham,

Nature Biomedical Engineering · 2023 · 90 citations · 37 references

DOI

Concepts

References

37

Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

Collin Edington, Wen Li Kelly Chen, Emily Geishecker et al. · Scientific Reports · 2018 · 470 citations · Full text

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A multi-organ chip with matured tissue niches linked by vascular flow

Kacey Ronaldson-Bouchard, Diogo Teles, Keith Yeager et al. · Nature Biomedical Engineering · 2022 · 444 citations · Full text

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Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs

Carlota Oleaga, Catia Bernabini, Alec S.T. Smith et al. · Scientific Reports · 2016 · 425 citations · Full text

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Robotic fluidic coupling and interrogation of multiple vascularized organ chips

Richard Novák, Susan Marquez, Debarun Das et al. · Nature Biomedical Engineering · 2020 · 403 citations · Full text

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Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury

William R. Proctor, Alison J. Foster, Jennifer Vogt et al. · Archives of Toxicology · 2017 · 318 citations · Full text

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