Manuel Weinheimer

Beyond Rule of Five and PROTACs in Modern Drug Discovery: Polarity Reducers, Chameleonicity, and the Evolving Physicochemical Landscape

Edward Price, Manuel Weinheimer, Alexey Rivkin et al. · Journal of Medicinal Chemistry · 2024 · 62 citations

Pharmaceutical Science, Drug Target, Chemical Biology +19

The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers — An in vitro and in vivo comparison

Manuel Weinheimer, Gert Fricker, Jürgen Burhenne et al. · European Journal of Pharmaceutical Sciences · 2016 · 27 citations

Lipid Preparation, Biochemistry, Medicine +6

Characterization and Validation of Canine P-Glycoprotein-Deficient MDCK II Cell Lines for Efflux Substrate Screening

Dong Ye, Anna Harder, Zhizhou Fang et al. · Pharmaceutical Research · 2020 · 18 citations

Protein Function, Biochemistry, Medicine +9

Mucin-Protected Caco-2 Assay to Study Drug Permeation in the Presence of Complex Biorelevant Media

Dong Ye, Álvaro López Mármol, Verena Lenz et al. · Pharmaceutics · 2022 · 13 citations · Full text

Conquering the beyond Rule of Five Space with an Optimized High-Throughput Caco-2 Assay to Close Gaps in Absorption Prediction

Patricia Muschong, Khader Awwad, Edward Price et al. · Pharmaceutics · 2024 · 12 citations · Full text